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The TLSR8258F1KET48A is Telink-developed Bluetooth LE + IEEE802.15.4 multi-standard wireless SoC solution with internal Flash and audio support, which combines the features and functions needed for all 2.4GHz IoT standards into a single SoC. It’s completely RoHS-compliant and 100% lead(Pb)-free.

USB2TTL

1 - 3V3
2 - X - RESETB（25）
3 - TXD - UART_TX（7） - PD<7>
4 - RTS - UART_RTS（5）
5 - GND

UART

#define RXD 		GPIO_PA7
#define TXD		GPIO_PD4

LED

#define LED_BLUE        GPIO_PD4
#define LED_RED		GPIO_PD3
#define LED_GREEN	GPIO_PB1

EPD

HINK-E042A76-A0：SSD1680

#define EPD_ENABLE	GPIO_PA0
#define EPD_MOSI		GPIO_PB7
#define EPD_CLK		GPIO_PD7
#define EPD_CS		GPIO_PD2
#define EPD_DC 		GPIO_PB6
#define EPD_RESET 	GPIO_PB5
#define EPD_BUSY 	GPIO_PC6

https://wiki.telink-semi.cn/wiki/chip-series/TLSR825x-Series/

Datasheet for Telink BLE + IEEE802.15.4 Multi-Standard Wireless SoC TLSR8258F1KET48A

Datasheet for Telink ULP 2.4GHz RF SoC TLSR8359

https://www.hanshow.com/zh-cn/nebular#specifications